Mechanism underlying sevoflurane-induced protection in cerebral ischemia–reperfusion injury

Abstract Cerebral ischemia is an extremely complex disease that can be caused by a variety of factors. cause great harm to human body. Sevoflurane volatile anesthetic frequently used in clinic, and has lot advantages, such as quick induction general anesthesia, anesthesia recovery, no respiratory tract irritation, muscle relaxation, small cycle effect. The mechanism sevoflurane preconditioning or post-treatment poorly understood. purpose this study was illustrate the underlying sevoflurane-induced protection cerebral ischemia–reperfusion injury also provide theoretical guidance for future research.